Characterization and Preliminary Correction of the FXPOI Phenotype in the 130-Repeat Fragile X Premutation Mouse

Date:

Research update talk at the Third International Conference on FMR1 Premutation, Jerusalem, Israel. I will cover the lab’s data on using CRISPR/Cas9 genome editing to alter and correct Fragile X Premutation alleles in a mouse model harboring 130 CGG repeats.